REFICIO DBM Putty provides exceptional handling without the need for excessive amounts of carrier, so there is space for more allograft, and thus more osteoinductive potential.38,39



Reficio is 74% DBM by weight40

The REFICIO Difference

  • 74% DBM by weight40
  • Assured osteoinductive response38,39
  • Substantially equivalent to iliac crest bone graft (ICBG)41
  • Exceptional handling characteristics
  • Ready to use

Exceptional Handling

  • Unique handling characteristics make it easy to use and resists migration under direct irrigation
  • Comes ready for use in a Luer-lok syringe and provides a flowable consistency
  • CMC (carboxymethyl cellulose) carrier is familiar, biocompatible, and has potential to stimulate bone growth42


Backed by Evidence

  • Shown to be substantially equivalent to ICBG in a preclinical spinal fusion model42
  • In vivo osteoinductive response tested in all final lots38,39
  • Extreme temperature study showed no adverse affect on the handling characteristics or the in vivo osteoinductivity of the product40


Economically Beneficial

  • Multiple volume options to minimize excess
  • Value option caters to all institutions, including ambulatory surgery centers (ASCs)
  • Off-the-shelf and ready to use: no storage or preparation needed



Request More Information

To request more information on REFICIO, or to contact your local Bioventus Surgical representative to order, please fill out this form.

Instructions For Use
REFICIO Instructions for use

Material Management Packet
REFICIO Material Management Packet



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